One out of every four adults is affected by sedentary habits, increasing the risk of cardiovascular disease, obesity, diabetes, and mortality. Indicators of concern include not meeting global health guidelines, spending more than half of waking hours inactivity, experiencing persistent fatigue, observing changes in weight and metabolism, and feeling easily winded. To address this, incorporate breaks in prolonged inactivity by standing, walking, or exercising for 3-6 minutes every hour.